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Publications

  • AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma

    Angelov D, Nolan J, Holland G, Nimmo D, Davies M, Monger C, Dillon E, Mucha M, Wang C, Gannon D, Lagan E, Malcolm A, Yang L, Chen A, Vandenberghe E, Flaus A, Chen CW, Brien GL, Conway E, Bracken AP.

    Paper Here

  • Dominant-negative effects of Weaver syndrome-associated EZH2 variants

    Deevy O, Li J, Monger C, Matrà F, Tuck E, Davies M, Badonyi M, Boyce M, Doyle EJ, Hokamp K, Nimmo D, Rodighiero S, Zhang Q, Davidovich C, Marsh JA, Pasini D, Conway E, Bracken AP.

    Paper Here

  • A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells

    McCole R, Nolan J, Reck DM, Monger C, Rustichelli S, Conway E, Brien GL, Wang C, Deevy O, Neikes HK, Bashore FM, Mooney A, Flavin R, Vandenberghe E, Flanigan SF, Pasini D, Davidovich C, Vermeulen M, James LI, Healy E, Bracken AP.

    Paper Here

  • Short circuit: Transcription factor addiction as a growing vulnerability in cancer

    Davies M, Boyce M, Conway E.

    Paper here

  • Editorial overview: 3D Genome Chromatin organization and regulation

    Conway E, Larson DR.

    Paper Here

  • Dominant negative effects on H3K27 methylation by Weaver syndrome-associated EZH2 variants

    Deevy, O. Monger, C. Matra, F. Tuck, E. Conway, E. Rodighiero, S. Zhang, Q. Davidovich, C. Pasini, D. Bracken A.P.

    Paper here

  • KNOW WHEN TO FOLD ‘EM: POLYCOMB COMPLEXES IN ONCOGENIC 3D GENOME REGULATION

    Doyle, E.J. Morey, L. Conway, E.

    Paper here

  • BAP1 ENHANCES POLYCOMB REPRESSION BY COUNTERACTING WIDESPREAD H2AK119UB1 DEPOSITION AND CHROMATIN CONDENSATION.

    Conway, E. Rossi, F. Fernandez-Perez, D. Ponzo, E. Ferrari, K,J. Zanotti, M. Manganaro, D. Rodighiero, S. Tamburri. Pasini, D.

    Paper here

  • Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer

    Tamburri, S. Conway, E. Pasini, D.

    Paper here

  • HISTONE H2AK119 MONO-UBIQUITINATION IS ESSENTIAL FOR POLYCOMB-MEDIATED TRANSCRIPTIONAL REPRESSION

    Tamburri, S. Lavarone, E. Fernandez-Perez, D. Conway, E. Zanotti, M. Manganaro, D. Pasini, D.

    Paper here

  • PRC2. 1 AND PRC2. 2 SYNERGIZE TO COORDINATE H3K27 TRIMETHYLATION

    Healy, E. Mucha, M. Glancy, E. Fitzpatrick, D.J. Conway, E. Neikes, H. Monger, C. Van Mierlo, G. Baltissen, M.J. Koseki, Y. Vermeulen, M. Koseki, H. Bracken, A.P.

    Paper here

  • A FAMILY OF VERTEBRATE-SPECIFIC POLYCOMBS ENCODED BY THE LCOR/LCORL GENES BALANCE PRC2 SUBTYPE ACTIVITIES

    Conway, E. Jerman, E., Healy, E., Ito, S., Holoch, D., Oliviero, G., Deevy, O., Glancy, E., Fitzpatrick, D.J., Mucha, M., Watson, A., Rice, A.M, Chammas, P., Huang, C., Pratt-Kelly, I., Koseki, Y., Nakayama, M., Ishikura, T., Streubel, G., Wynne, K., Hokamp, K., McLysaght, A., Ciferri, C., Di Croce, L., Cagney, G., Margueron, R., Koseki, H., Bracken, A.P.

    Paper here

  • THE H3K36ME2 METHYLTRANSFERASE NSD1 DEMARCATES PRC2-MEDIATED H3K27ME2 AND H3K27ME3 DOMAINS IN EMBRYONIC STEM CELLS

    Streubel, G., Watson, A., Jamulla, S.G., Scelfo, A., Fitzpatrick, D.J., Oliviero, G., McCole, R., Conway, E., Glancy, E., Luca Negri, G., Dillon, E., Wynne, K., Pasini, D., Krogan, N.J., Bracken, A.P., Cagney, G.

    Paper here

  • UNRAVELING THE ROLES OF CANONICAL AND NONCANONICAL PRC1 COMPLEXES

    Conway, E. and Bracken, A.P.

    Paper here

  • PRC2 MEDIATED H3K27 METHYLATIONS IN CELLULAR IDENTITY AND CANCER

    Conway, E., Healy, E., and Bracken, A.P.

    Paper here

  • A CHROMATIN-INDEPENDENT ROLE OF POLYCOMB-LIKE 1 TO STABILIZE P53 AND PROMOTE CELLULAR QUIESCENCE

    Brien, G.L., Healy, E., Jerman, E., Conway, E., Fadda, E., O'Donovan, D., Krivtsov, A.V., Rice, A.M., Kearney, C.J., Flaus, A., et al.

    Paper here

Contact us: eric.conway@ucd.ie

School of Biomolecular and Biomedical Sciences,

University College Dublin, Belfield, Dublin 4